13
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T21859 | ARM1 | Aminopeptidase , Epoxide Hydrolase | |
ARM1 is a potent inhibitor of aminopeptidase and epoxide hydrolase. The IC50 values are 7.61 µM for aminopeptidase and 12.4 µM for epoxide hydrolase. | |||
T41319 | D-Saccharic acid 1,4-lactone hydrate | Others | |
D-Saccharic acid 1,4-lactone hydrate is a potent β-glucuronidase inhibitor (IC50=48.4 μM). D-Saccharic acid 1,4-lactone hydrate possesses anticarcinogenic, detoxifying, and antioxidant properties[1][2]. | |||
T14571 | Bifenazate | GABA Receptor | |
Bifenazate is a positive allosteric modulator of GABA receptor. Bifenazate is an acaricide that controls 100% of mites at a concentration of 25 ppm. | |||
T40296 | MCA17-1 | MCA17-1 | |
MCA17-1 exhibits superior bioactivity compared to the positive control, obeticholic acid (OCA), in the treatment of liver fibrosis. | |||
TN3056 | 4-O-Galloylbergenin | Others | |
4-O-Galloylbergenin shows significant 2,2-diphenyl-1-picrylhydrazyl (DPPH) free-radical scavenging activity with EC50 7.8 uM, it shows more antioxidant activity than the positive control vitamin C (EC50 = 28.3 uM). | |||
TN5154 | Torilolone | Others | |
Torilin and torilolone show hepatoprotective effects on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells,the EC50 values are 20.6 +/- 1.86 and 3.6 +/- 0.1 microM, respectively; and silybin as a positive c... | |||
T82398 | Firefly Luciferase circRNA | ||
Firefly Luciferase circRNA, originally isolated from Photinus pyralis (Firefly), expresses a luciferase protein and serves as an optimal marker for monitoring and optimizing transfection efficiency; it is also recommende... | |||
T71097 | DC-120 | ||
DC-120 is an ATP competitive AKT kinase inhibitor that suppressed proliferation and induced apoptosis in liver cancer cells both in vitro and in vivo. DC120 blocked the phosphorylation of downstream molecules in the AKT ... | |||
TN1606 | (-)-Epiafzelechin | COX | |
(-)-Epiafzelechin exhibits significant anti-inflammatory activity on carrageenin-induced mouse paw edema, it exhibits a dose-dependent inhibition on the COX activity with an IC50 value of 15 microM, it exhibits about 3-f... | |||
T82497 | EGFP circRNA | ||
eGFP circRNA, originally isolated from the jellyfish Aequorea victoria, is a reporter widely utilized for direct detection in mammalian cell culture due to its bright green fluorescence with an emission peak at 509 nm. I... | |||
T35422 | 5'-pApA (sodium salt) | ||
5'-pApA is a linearized form of cyclic di-AMP, a bacterial second messenger that activates the host innate immune system through stimulator of interferon genes (STING).1,2,3,4It is a metabolite of cyclic di-AMP formedvia... | |||
T67442 | CGP-53716 | ||
The growth factors, platelet-derived growth factor (PDGF) and basic fibroblast growth factor (bFGF) play major roles in enhanced smooth muscle cells growth in rodent blood vessels after vascular injury. Tyrosine kinase i... | |||
T36629 | Givinostat | ||
Givinostat (ITF-2357) is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. Givinostat (ITF2357) suppresses total LPS-induced IL-1β production robustly compared with the reduction by ITF30... |